Under the direction of a Principal Investigator, further develops and expands understanding of scientific theory in his/her area of interest. Incumbent also learns and applies scientific laboratory techniques and gains experience in other areas of research that will lead to increased probability of success as an independent scientist. This is a training position with an expected duration of 1 – 3 years.  The Pulikkan Lab focuses on uncovering the mechanisms of leukemogenesis and identifying novel therapeutic targets in CEBPA mutant and inv(16) acute myeloid leukemia (AML). Recently, the lab developed the first conditional knock-in mouse model for CEBPA mutations in AML. Successful candidates will work on projects related to the therapeutic targeting of chromatin deregulation in...

Under direct supervision by department leadership, performs CLIA regulated and clinical contract research testing. Interacts at a basic level with customers, providing a high level of customer service to resolve customer concerns about sample acceptability and results. Supports preparation of laboratory reagents and routine maintenance of laboratory equipment .

Provides data analysis, integration, and development of new computational methods to analyze and integrate genome wide datasets from transcriptome, epigenomic, and other types of functional genomics-based approaches.

Under direct supervision by department leadership, performs CLIA regulated and clinical contract research testing. Interacts at a basic level with customers, providing a high level of customer service to resolve customer concerns about sample acceptability and results. Supports preparation of laboratory reagents and routine maintenance of laboratory equipment .

Performs laboratory assays and complex experiments to elucidate novel research questions. The Xian Lab studies how mitochondrial stress controls cellular immunology in autoimmune diseases, Alzheimer's disease and cancer. We address how the immune sensing of mitochondrial DNA licenses inflammation and autoimmunity. We integrate functional genomics and proteomics with cellular and molecular immunology techniques, to understand the crosstalk between dendritic cells, CD4 T cells and macrophages. Ideal candidates will have skills in animal handling, lab management skills, strong commnication, and basic cellular/molecular skills in genotyping, PCR, flow cytometry, ELISA, cell immunofluourescence, Western blotting, cell culture, etc.

Under the direction of the assigned executive, provides advanced administrative support to the executive and provides support to the executive's areas of responsibilities.

Under direction of the Manager of Transfusion Service, follows all applicable SOPs, performs immunohematology testing on patient samples and provides the correct blood product for transfusion based on these results. Performs component preparation as ordered by the provider to ensure the correct product is issued for transfusion. Provides the most appropriate blood in a timely and accurate manner and provides phone consultation to customers.

Under direct supervision by department leadership, performs CLIA regulated and clinical contract research testing. Interacts at a basic level with customers, providing a high level of customer service to resolve customer concerns about sample acceptability and results. Supports preparation of laboratory reagents and routine maintenance of laboratory equipment .

Under the direction of a Principal Investigator, further develops and expands understanding of scientific theory in his/her area of interest. Incumbent also learns and applies scientific laboratory techniques and gains experience in other areas of research that will lead to increased probability of success as an independent scientist. This is a training position with an expected duration of 1 year.  This project is part of our NIH R01 grant focused on defining how endothelial Rap1 isoforms regulate calcium and nitric oxide signaling to support EC–cardiomyocyte communication during cardiac growth and stress. We use endothelial-specific knockout mice, calcium imaging, vascular physiology, and endothelial cell – cardiomyocyte co-culture models to uncover mechanisms by which Rap1...

Develops, improves, and implements laboratory techniques and performs complex experiments and/or tests to contribute to the timely and accurate completion of the research project(s). This project is part of our NIH R01 grant focused on defining how endothelial Rap1 isoforms regulate calcium and nitric oxide signaling to support EC–cardiomyocyte communication during cardiac growth and stress. We use endothelial-specific knockout mice, calcium imaging, vascular physiology, and endothelial cell – cardiomyocyte co-culture models to uncover mechanisms by which Rap1 dysfunction impairs coronary flow and promotes heart failure.

Under the direction of Diagnostic Laboratory leadership, and in partnership with the Director of Hemostasis and Medical Directors of Hematology (Hemostasis, Platelet & Neutrophil Immunology (PNIL), and Hematology Genetics (HG)), provides scientific, technical, and clinical direction to the Hemostasis Laboratory as well as leadership and management to the laboratory in collaboration with administrators of laboratory operations; responsible for providing scientific consultation and guidance related to clinical and contract research, product development and specific business and strategic initiatives. Areas of focus include scientific and clinical leadership, review and sign-out of patient reports, staff development, and operational excellence, driving innovation, continuous improvement, and...

Develops, improves, and implements laboratory techniques and performs complex experiments and/or tests to contribute to the timely and accurate completion of the research project(s). The Xian Lab studies how mitochondrial stress controls cellular immunology in autoimmune diseases, Alzheimer's disease and cancer. We address how the immune sensing of mitochondrial DNA licenses inflammation and autoimmunity. We integrate functional genomics and proteomics with cellular and molecular immunology techniques, to understand the crosstalk between dendritic cells, CD4 T cells and macrophages. Ideal candidates will have skills in animal handling, lab management skills, strong commnication, and basic cellular/molecular skills in genotyping, PCR, flow cytometry, ELISA, cell immunofluourescence,...

Develops, improves, and implements laboratory techniques and performs complex experiments and/or tests to contribute to the timely and accurate completion of the research project(s). The Jarjour lab studies tissue-resident immunity to pathogens, including viruses, bacteria, and helminths. Tissue-resident T cells are an area of special emphasis. This position will play an important role in launching the laboratory with primary responsibilities for managing/genotyping the mouse colony and ordering, as well as assisting with experiments and other more minor responsibilities. While prior laboratory experience is required, training will be provided in the specific techniques required for the position. Ideal candidates will have experience with animal handling, techniques, and euthanasia;...

Under direction of the Manager of Transfusion Service, follows all applicable SOPs, performs immunohematology testing on patient samples and provides the correct blood product for transfusion based on these results. Performs component preparation as ordered by the provider to ensure the correct product is issued for transfusion. Provides the most appropriate blood in a timely and accurate manner and provides phone consultation to customers.

Under direction of the Manager of Transfusion Service, follows all applicable SOPs, performs immunohematology testing on patient samples and provides the correct blood product for transfusion based on these results. Performs component preparation as ordered by the provider to ensure the correct product is issued for transfusion. Provides the most appropriate blood in a timely and accurate manner and provides phone consultation to customers.

Under direct supervision by department leadership, performs CLIA regulated and clinical contract research testing. Interacts at a basic level with customers, providing a high level of customer service to resolve customer concerns about sample acceptability and results. Supports preparation of laboratory reagents and routine maintenance of laboratory equipment .

Under the direction of a Principal Investigator, further develops and expands understanding of scientific theory in his/her area of interest. Incumbent also learns and applies scientific laboratory techniques and gains experience in other areas of research that will lead to increased probability of success as an independent scientist. This is a training position with an expected duration of 1 – 3 years.  The Sundd Lab is an NIH-funded lab that studies the role of inflammasome, nucleic acid sensing and interferon signaling in neutrophils and platelets in the pathophysiology of vaso-occlusion, lung injury and sterile inflammation in Sickle Cell Disease. The prospective candidate will have the opportunity to learn state-of-the-art techniques such as Multi-Photon-Excitation intravital...

Under the direction of the Senior Director, Histocompatibility, Versiti DL, is accountable for helping to provide leadership and guide direction of the Histocompatibility Laboratories across Versiti, with a focus on clinical care, diagnostic innovation, education, and operational excellence. Contributes to the development and successful execution of business and strategic initiatives; contributes to managing the people and financial resources; contributes to ongoing and sustainable improvement in the areas of compliance, customer/employee satisfaction, and process improvement. Provides assistance to the Senior Director of Histocompatibility, as requested.