Learns about the scientific approach to research questions, records laboratory data in an established format, and performs simple standard laboratory research procedures

Under the direction of the Director, Microscopy Core Laboratories assists researchers with experimental planning, microscope operation, and image acquisition across a range of imaging platforms and sample types. The Imaging Specialist provides user training, ensures proper instrument use, data analysis,and contributes to the maintenance of microscopes. Works independently; has a strong background in fluorescence microscopy and familiarity with advanced imaging approaches such as confocal, multiphoton, or intravital microscopy.

The Flow Cytometry technologist/specialist works under the direction of the Flow Cytometry Core leader and the Director of Shared Resources to (1) help maintain cytometry and similar instrumentation (cell analyzers and sorters); (2) develop/improve/implement lab techniques and perform complex experiments (cytometry panel design, sample processing, data acquisition, cell sorting, data analysis); and (3) interface with the broad userbase to provide scientific expertise, cytometry-focused training/education, experimental and instrument troubleshooting, and interpret experimental outcomes to contribute to the timely and accurate completion of research projects. This individual will work as part of the Flow Cytometry Core team to facilitate completion of lab operations and provide services for...

Under the direction of a Principal Investigator, further develops and expands understanding of scientific theory in his/her area of interest. Incumbent also learns and applies scientific laboratory techniques and gains experience in other areas of research that will lead to increased probability of success as an independent scientist.  The Gu Laboratory at the VBRI is seeking a highly motivated Postdoctoral Fellow in Computational Biology, Artificial Intelligence, and Multi-Omics Data Science. This position offers an exciting opportunity to develop and apply cutting-edge machine learning, deep learning, and statistical approaches to uncover the molecular mechanisms of cancer and other complex diseases. Our research focuses on integrative analysis of large-scale multi-omics datasets,...

Performs laboratory assays and complex experiments to elucidate novel research questions. The Ma Lab studies integrin signaling in blood cells. Integrin family receptors deliver bidirectional signaling (inside-out and outside-in) across the cell plasma membrane, modulating cell adhesion, migration, proliferation, differentiation, and other functions. Integrin signaling involves a series of molecular events within cells that enable integrins to bridge the crosstalk between the extracellular milieu and cytoskeletal changes, as well as cytoplasmic signaling cascades. Integrin activation is tightly regulated by integrin cytoplasmic tail binding proteins (ICBPs). The interaction between integrins and ICBPs defines the activation states and functional activities of integrins. Dysfunction of...

Performs laboratory assays and complex experiments to elucidate novel research questions. The Zhu Lab is primarily focused on unraveling the mechanisms of receptor transmembrane signaling. Specifically, our attention is directed towards cell surface receptors featuring single transmembrane domains, such as integrins, receptor tyrosine kinases, and receptor-like tyrosine phosphatases. Through a multidisciplinary approach encompassing structural biology, protein engineering, biochemistry, and cell biology techniques, we aim to elucidate how these receptors transmit signals across the cell membrane. Our investigations center on understanding the conformational regulation triggered by ligand binding at the extracellular domain or cytoplasmic domain stimulations. Our goal is to illustrate...

Under the direction of a Principal Investigator, further develops and expands understanding of scientific theory in his/her area of interest. Incumbent also learns and applies scientific laboratory techniques and gains experience in other areas of research that will lead to increased probability of success as an independent scientist. This is a training position with an expected duration of 1 – 3 years.  The Falet Lab focuses on deficient platelet production, due to genetic causes, secondary to cancer therapy, or from unknown etiology, poses significant risks of mortality, mostly due to bleeding. Our primary research interests are associated with deciphering the cellular mechanisms and proteins regulating normal and abnormal blood platelet production and function.

About VBRI and its Immunology ResearchThe Versiti Blood Research Institute (VBRI) is a private research institute and leader in blood-related research, spanning fundamental mechanisms to clinical and translational studies. Home to 30 principal investigators, the faculty benefit from a research-focused environment with minimal teaching obligations while mentoring graduate students and postdoctoral fellows. As part of a strategic growth initiative, VBRI plans to recruit 18 new faculty members over the next 5–7 years and complete a state-of-the-art expansion (60,000–80,000 ft²) by the end of 2026.VBRI immunologists conduct collaborative research on autoimmunity; B, T, and NK cell biology; and immune regulation, with opportunities for cross-disciplinary collaboration. They have access...

Develops and elucidates scientific aims, experimental design and execution. A Research Scientist I is equivalent to the Research Assistant Professor position at many universities. The Zhu Lab is primarily focused on unraveling the mechanisms of receptor transmembrane signaling. Specifically, our attention is directed towards cell surface receptors featuring single transmembrane domains, such as integrins, receptor tyrosine kinases, and receptor-like tyrosine phosphatases. Through a multidisciplinary approach encompassing structural biology, protein engineering, biochemistry, and cell biology techniques, we aim to elucidate how these receptors transmit signals across the cell membrane. Our investigations center on understanding the conformational regulation triggered by ligand binding...

Under the direction of a Principal Investigator, further develops and expands understanding of scientific theory in his/her area of interest. Incumbent also learns and applies scientific laboratory techniques and gains experience in other areas of research that will lead to increased probability of success as an independent scientist. This is a training position with an expected duration of 1 – 3 years.  At the crossroads of metabolism, immunity, and aging The Xian lab’s long-term goal is to enhance immune therapies by uncovering how mitochondrial stress activates the immune system. We focus on how mitochondria-released danger signals—known as danger-associated molecular patterns (DAMPs)—shape immunity. In particular, we study circulating oxidized mitochondrial DNA (Ox-mtDNA),...

Faculty Positions in Basic and/or Translational Blood ResearchWe seek to grow our Transfusion Medicine, Vascular Biology and Cell Therapy Program by recruiting innovative investigators with research interests in blood research and related fields such as transfusion science, cell therapy, gene therapy, glycobiology, and vascular biology. Applicants at all academic ranks with Ph.D., M.D., or equivalent degrees are encouraged to apply. Ideal candidates will develop or maintain independently funded basic and/or translational research programs. These positions provide attractive start-up packages and outstanding opportunities for collaboration with basic, translational, and clinical investigators. The VBRI is located on the same campus as the Medical College of Wisconsin (MCW), Children’s...